SMB chromatography simulation

feed + desorbent -> extract + raffinate (True Moving Bed equivalent)

Governing equations

The exact equations the solver works for a smb chromatography — the same math shown in the app's "Theory" panel, not a black box.

$q_i$

adsorbed concentration of i

$c_i$

fluid-phase concentration of i

$H_i$

linear-isotherm Henry constant — the two components' H values are the separation

$H_{weak}, H_{strong}$

the less- and more-retained solute's Henry constants

$m_j$

flow-rate ratio in zone j — the design variables you actually tune

$Q_j$

fluid flow in zone j

$Q_s$

solid (port-switch) flow

Parameters

isotherms {component: {H}} (linear) or {component: {q_max, b}} (Langmuir); optional m_values [m1,m2,m3,m4] zone flow ratios (default a triangle-feasible set), n_stages_per_zone [int, default 8]. Two inlets (feed, desorbent) -> extract (strongly-retained) + raffinate (weakly-retained) via the steady-state True Moving Bed equivalent

Example flowsheets that use it