Bioprocesses as real unit operations
Perfusion culture where retention genuinely decouples cell density from medium exchange, Monod fermentation with its washout limit, continuous simulated-moving-bed chromatography and chemolithoautotrophic gas fermentation — native models, not spreadsheets bolted onto a flowsheet.
Process modules
Continuous mAb culture where a retention device holds cells back, so a deliberate bleed sets density rather than the medium-exchange rate.
Open process page →Media conditioning and a Monod chemostat solved together, with the washout limit falling out of the kinetics.
Open process page →A racemic API resolved continuously by simulated moving bed — counter-current contacting without moving any solids.
Open process page →Hydrogen-oxidizing bacteria fixing CO₂ into single-cell protein, closing the gas and liquid balances together.
Open process page →Two of these are things legacy steady-state simulators have no native model for at all: continuous SMB chromatography (usually scripted in MATLAB alongside the flowsheet) and perfusion with cell retention (an ordinary chemostat structurally cannot represent it). Each carries a collapse gate to a model already in the tree — perfusion at zero retention reproduces the chemostat exactly. No organism, resin or medium data ships; those are measured per process.